Fig. 1 · Structure
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LabMol-319
ZIKV NS5 RdRp Inhibitor
LabMol-319 is a potent inhibitor of the Zika virus (ZIKV) non-structural protein 5 (NS5) RNA-dependent RNA polymerase (RdRp) with an IC50 of 1.6 μM. This compound demonstrates significant antiviral activity, making it a valuable tool for research aimed at understanding ZIKV replication and developing therapeutic strategies against Zika virus infections. Its efficacy in targeting viral polymerase positions LabMol-319 as an essential reagent in virology and antiviral research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 381188-63-2 |
| Applications | ZIKV NS5 RdRp Inhibitor |
| Formula | C22H16N2O5 |
| Molecular Weight | 388.37 |
| SMILES | O=C(C1=CC=CC(N2C(C3=CC=C(C=C3C2=O)OC4=CC=C(C=C4)N)=O)=C1)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.