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Lacnotuzumab
Lacnotuzumab (MCS110) is a humanized IgG1/κ monoclonal antibody that selectively targets colony-stimulating factor 1 (CSF-1), effectively blocking its interaction with the CSF-1 receptor (CSF-1R). This neutralization impedes CSF-1R activation, which is crucial in various cellular processes. Lacnotuzumab is primarily utilized in research focused on pigmented villonodular synovitis, providing valuable insights into the pathophysiology and potential therapeutic targets of this disease.
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Biological Activity
Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1831128-32-5 |
| Synonyms | MCS110 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.