Fig. 1 · Structure
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Lactisole
T1R3 Antagonist
Lactisole is a specific antagonist of the sweet taste receptor, primarily targeting the T1R3 subunit, which is involved in glucose sensing. It exhibits the ability to inhibit glucose-induced insulin secretion in murine pancreatic islets. This compound serves as a valuable tool for research applications related to metabolic function and glucose homeostasis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 150436-68-3 |
| Applications | T1R3 Antagonist |
| Formula | C10H11NaO4 |
| Molecular Weight | 218.18 |
| SMILES | COC1=CC=C(C=C1)OC(C(O[Na])=O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.