Documents & Downloads

Ladirubicin

Antitumor Agent

Ladirubicin (PNU-159548) is an antitumor agent derived from Daunorubicin. It functions through DNA intercalation and alkylation, effectively inhibiting DNA replication and transcription, leading to significant DNA damage and antitumor activity. With its high lipophilicity, Ladirubicin has the potential to penetrate the blood-brain barrier, making it a candidate for treating central nervous system tumors. However, it is important to note that Ladirubicin can exhibit toxicity by suppressing bone marrow activity.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
CAS Number	171047-47-5
Applications	Antitumor Agent
Formula	C₂₉H₃₁NO₁₁S
Molecular Weight	601.62
Synonyms	PNU-159548
SMILES	C[C@H]1[C@@H](OS(C)(=O)=O)[C@@H](N2CC2)C[C@](O1)([H])O[C@@H]3C4=C(O)C(C(C5=CC=CC=C5C6=O)=O)=C6C(O)=C4C[C@](C(C)=O)(O)C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.