Fig. 1 · Structure
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Lamotrigine-13C3,d3
Stable Isotope
Lamotrigine-13C3,d3 is a stable isotope-labeled derivative of Lamotrigine, a potent anticonvulsant agent that selectively inhibits voltage-gated Na+ channels. This action stabilizes presynaptic neuronal membranes and reduces glutamate release, making it a critical tool in studying the mechanisms of epilepsy and focal seizures. Lamotrigine-13C3,d3 is suitable for applications in metabolic studies and pharmacokinetics, enhancing the understanding of Lamotrigine’s therapeutic effects and its metabolic pathways in neurological research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1246815-13-3 |
| Applications | Stable Isotope |
| Formula | C613C3H4D3Cl2N5 |
| Molecular Weight | 262.09 |
| Synonyms | LTG-13C3; d3; BW430C-13C3 |
| SMILES | N[13C]1=N[13C](N)=NN=[13C]1C2=C(C(Cl)=C([2H])C([2H])=C2[2H])Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.