Fig. 1 · Structure
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Lamotrigine-d3
Stable Isotope
Lamotrigine-d3 is a deuterium-labeled analog of Lamotrigine, which functions primarily as an anticonvulsant by selectively blocking voltage-gated Na+ channels. This mechanism stabilizes presynaptic neuronal membranes and reduces glutamate release, making it relevant for research into epilepsy and focal seizures. As a stable isotope, Lamotrigine-d3 is suitable for tracer studies in pharmacokinetics and metabolic research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1132746-94-1 |
| Applications | Stable Isotope |
| Formula | C9H4D3Cl2N5 |
| Molecular Weight | 259.11 |
| Synonyms | LTG-d3; BW430C-d3 |
| SMILES | NC1=NC(N)=C(C2=C(Cl)C(Cl)=C([2H])C([2H])=C2[2H])N=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.