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LANA

KSHV Latency-Associated Nuclear Antigen

LANA (Latency-Associated Nuclear Antigen) functions as a critical anchor for the Kaposi's Sarcoma Herpesvirus (KSHV) genome, facilitating its attachment to host cell chromatin. This mechanism ensures the synchronized replication of episomal KSHV DNA with the host chromosome, thereby preserving the virus's latent state within the host cell population. LANA also plays a role in the regulation of both viral and host gene expression, contributing to cell survival. Research applications include investigating the viral DNA tethering structure and its implications in persistent viral infection and pathogenesis.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	878495-58-0
Applications	KSHV Latency-Associated Nuclear Antigen
Formula	C₉₅H₁₆₇N₃₅O₂₉S₃
Molecular Weight	2359.75

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.