Lanisidenib

Catalog No.: A75797
IDH Inhibitor
Lanisidenib is an isocitrate dehydrogenase (IDH) inhibitor that displays potent antineoplastic activity. By targeting abnormal IDH enzymes, it disrupts metabolic pathways involved in tumor growth and survival. This compound is applicable in research focused on cancer metabolism and therapeutic strategies for IDH-mutated malignancies.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLanisidenib is an isocitrate dehydrogenase (IDH) inhibitor that displays potent antineoplastic activity. By targeting abnormal IDH enzymes, it disrupts metabolic pathways involved in tumor growth and survival. This compound is applicable in research focused on cancer metabolism and therapeutic strategies for IDH-mutated malignancies.
Product Information
Catalog NumA75797
FormulaC28H23ClF3N5O4S
Molecular Weight618.03
CAS Number2135537-20-9
SMILESFC(F)(C1)CC1NC([C@H](C2=C(C=CC=C2)Cl)N(C3=CC(F)=CC=C3)C([C@H]4N(C5=CC(C#N)=CC=N5)S(=O)(CC4)=O)=O)=O
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