Lanosterol-d6

Catalog No.: A72836
Stable Isotope
Lanosterol-d6 is a deuterated form of lanosterol, a key intermediate in cholesterol biosynthesis. This stable isotope is instrumental in studying the metabolic pathways of cholesterol, as it induces the ubiquitination and degradation of HMG-CoA reductase, a rate-limiting enzyme in cholesterol synthesis. Research applications include investigating lipid metabolism and exploring mechanisms of cholesterol homeostasis.
Grouped product items
Size Price Stock Qty
100µg
$490.00
In stock
1mg
$2,425.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLanosterol-d6 is a deuterated form of lanosterol, a key intermediate in cholesterol biosynthesis. This stable isotope is instrumental in studying the metabolic pathways of cholesterol, as it induces the ubiquitination and degradation of HMG-CoA reductase, a rate-limiting enzyme in cholesterol synthesis. Research applications include investigating lipid metabolism and exploring mechanisms of cholesterol homeostasis.
Product Information
Catalog NumA72836
FormulaC30H44D6O
Molecular Weight432.75
CAS Number28290-39-3
SMILESC[C@]12C3=C(CC[C@@]1([C@@](CC2)([H])[C@H](C)CC/C=C(C([2H])([2H])[2H])/C([2H])([2H])[2H])C)[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC3)C
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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