Fig. 1 · Structure
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Larazotide
Zonulin Antagonist
Larazotide is a peptide that functions as an orally active antagonist of zonulin. It exhibits antiviral activity against the varicella-zoster virus (VZV), displaying EC50 values of 44.14 μM and 59.06 μM for strains OKA and 07-1, respectively. This reagent is primarily utilized in research related to celiac disease and viral infections, making it a valuable tool for studying intestinal permeability and immune response modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 258818-34-7 |
| Applications | Zonulin Antagonist |
| Formula | C32H55N9O10 |
| Molecular Weight | 725.83 |
| SMILES | C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC(CN)=O)=O)[C@H](C)C)=O)CC(C)C)=O)C(C)C)=O)CCC(N)=O)(=O)N1[C@H](C(NCC(O)=O)=O)CCC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.