Fig. 1 · Structure
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Larsucosterol ammonium
LXR Antagonist
Larsucosterol ammonium is a potent liver X receptor (LXR) antagonist derived from cholesterol metabolism. It effectively decreases lipogenesis and inhibits cholesterol biosynthesis by reducing mRNA levels, thus preventing the activation of sterol regulatory element-binding protein 1 (SREBP-1). This compound is valuable in research applications focused on metabolic disorders and lipid regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2655654-16-1 |
| Applications | LXR Antagonist |
| Formula | C27H49NO5S |
| Molecular Weight | 499.75 |
| Synonyms | DUR-928 ammonium |
| SMILES | C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)(O)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)OS(=O)(O)=O)=CC3)C.N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.