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Lauric Acid

Proton pump inhibitor

Lauric acid is a proton pump inhibitor potentially for the treatment of helicobacter pylori infections.

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Biological Activity

Target & Activity

Target	Activity	Value
Human Endogenous Metabolite

Cellular Effect

Cell Line	Activity	Value	Description	Reference
CHO	EC50	3.49 μM	Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment measured after 90 mins by beta-galactosidase based PathHunter assay	[PMID: 31721581]
CHO	EC50	8.87 μM	Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulated [3H]cAMP accumulation preincubated for 5 mins followed by forskolin stimulation and measured after 15 m	[PMID: 31721581]

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	143-07-7
Applications	Proton pump inhibitor
Formula	C₁₂H₂₄O₂
Molecular Weight	200.32
Synonyms	Dodecanoic Acid
SMILES	CCCCCCCCCCCC(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

Solvent	Reported Solubility
DMSO	40 mg/mL (199.68 mM)
Water	20 mg/mL (99.84 mM)
Ethanol	40 mg/mL (199.68 mM)

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.