LC3 liagnd-2

Catalog No.: A80704
Ligands for E3 Ligase
LC3 ligand-2 is a ligand for E3 ligases that facilitates targeted protein degradation through the PROTAC system. This compound is utilized in the synthesis of PROTAC PDEδ autophagic degrader 1, providing a valuable tool for researchers studying autophagy and protein homeostasis. Its application extends to the development of novel therapeutic strategies for diseases associated with protein misfolding and aggregation.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLC3 ligand-2 is a ligand for E3 ligases that facilitates targeted protein degradation through the PROTAC system. This compound is utilized in the synthesis of PROTAC PDEδ autophagic degrader 1, providing a valuable tool for researchers studying autophagy and protein homeostasis. Its application extends to the development of novel therapeutic strategies for diseases associated with protein misfolding and aggregation.
Product Information
Catalog NumA80704
FormulaC17H10Br2INO4
Molecular Weight578.98
CAS Number2839637-57-7
SMILESO=C(O)COC1=C(Br)C=C(/C=C2C(NC3=C\2C=C(I)C=C3)=O)C=C1Br
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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