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LCK degrader-3

LCK Degrader

LCK Degrader-3 is a CRBN-based molecular glue degrader targeting LCK (lymphocyte-specific protein tyrosine kinase). This compound facilitates the selective degradation of LCK, making it a valuable tool for investigating the role of LCK in acute lymphoblastic leukemia. Its application in research may provide insights into therapeutic mechanisms and potential treatment strategies for leukemia.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	3095032-59-7
Applications	LCK Degrader
Formula	C₂₄H₂₂N₄O₄
Molecular Weight	430.46
SMILES	O=C(C(N1)=C(CC)C2=C1C=CC=C2)NC3=CC4=C(C(N(C(CC5)C(NC5=O)=O)C4)=O)C=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.