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Lck-IN-2

Lck inhibitor

Lck-IN-2 is a potent inhibitor of Lymphocyte-specific protein tyrosine kinase (Lck) with an IC50 value of 10.6 nM. This compound demonstrates significant antitumor activity in colon cancer cells, with GI50 values ranging from 0.24 to 1.26 μM. In Colo201 cells, Lck-IN-2 induces apoptosis, highlighting its potential for research applications in cancer therapeutics and cellular signaling studies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2615173-24-3
Applications	Lck inhibitor
Formula	C₃₁H₃₂N₈O₅
Molecular Weight	596.64
SMILES	CC1=CC=C(C=C1N2CC3=C(N(C2=O)C)N=C(N=C3)NC4=CN=C(C=C4)C)NC(C5=CC=C(C(OCC(C)C)=C5)[N+]([O-])=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.