Fig. 1 · Structure

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LCK ligand-1

LCK Ligand

LCK Ligand-1 is a ligand that specifically targets LCK, a crucial protein involved in T-cell activation and signaling. This compound functions as a building block for the synthesis of the PROTAC degrader SJ45566, facilitating targeted protein degradation in research applications. It is essential for studies focused on modulating LCK activity and exploring its role in various cellular processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 823206-99-1
Applications LCK Ligand
Formula C16H14ClN5OS
Molecular Weight 359.83
SMILES
O=C(NC1=C(Cl)C=CC=C1C)C(S2)=CN=C2NC3=CC=NC(C)=N3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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