LCL-161

Catalog No.: A11928

Antagonist of IAPs inhibitor

LCL-161

LCL-161 Chemical Structure

CAS NO. 1005342-46-0

LCL161 is an orally bioavailable second mitochondrial-derived activator of caspases (SMAC) mimetic and inhibitor of IAP (Inhibitor of Apoptosis Protein) family of proteins, with potential antineoplastic activity.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $60.00

Special Price $48.00

10 mg

Regular Price: $100.00

Special Price $80.00

25 mg

Regular Price: $180.00

Special Price $144.00

10mM * 1mL in DMSO
$119.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

LCL161 is an orally bioavailable second mitochondrial-derived activator of caspases (SMAC) mimetic and inhibitor of IAP (Inhibitor of Apoptosis Protein) family of proteins, with potential antineoplastic activity.
Targets
cIAP XIAP
In vitro DMSO 100 mg/mL (199.74 mM)
Water <1 mg/mL (<1 mM)
Ethanol 20 mg/mL heating (39.94 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.99 mL 99.96 mL 199.92 mL
0.5 mM 4 mL 19.99 mL 39.98 mL
1 mM 2 mL 10 mL 19.99 mL
5 mM 0.4 mL 2 mL 4 mL

*The above data is based on the productmolecular weight 500.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A11928
Actions Antagonist
M. Wt 500.2
Formula C26H33FN4O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1005342-46-0
Synonyms LCL161, LCL 161
SMILES C[[email protected]@H](C(=O)N[[email protected]@H](C1CCCCC1)C(=O)N2CCC[[email protected]]2C3=NC(=CS3)C(=O)C4=CC=C(C=C4)F)NC

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