Fig. 1 · Structure
Documents & Downloads
LCS-1
SOD1 Inhibitor
LCS-1 is a specific inhibitor of superoxide dismutase 1 (SOD1), demonstrating an IC50 value of 1.07 μM for SOD1 activity. This compound induces both early- and late-stage apoptosis in multiple myeloma (MM.1S) cells, making it a valuable tool for research into the mechanisms of cell survival and death in oncological studies. Its application in studying the role of oxidative stress and SOD1 in cancer biology provides insights into potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 41931-13-9 |
| Applications | SOD1 Inhibitor |
| Formula | C11H8Cl2N2O |
| Molecular Weight | 255.10 |
| SMILES | O=C1C(Cl)=C(Cl)C=NN1C2=CC=CC(C)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.