LDC1267

Catalog No.: A13003

TAM Receptor inhibitor

LDC1267

LDC1267 Chemical Structure

CAS NO. 1361030-48-9

LDC1267 is a highly selective TAM(Tyro3, Axl and Mer) kinase inhibitor with IC50 of <5 nM/8 nM/29 nM for Tyro3,Axl and Mer respectively.

Availability: In stock

Package Price Qty
5 mg
$70.00
10 mg
$110.00
25 mg
$220.00
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Biological Activity

LDC1267 is a highly selective TAM(Tyro3, Axl and Mer) kinase inhibitor with IC50 of <5 nM/8 nM/29 nM for Tyro3,Axl and Mer respectively.
Targets
Mer Tyro3 Axl
<5 nM8 nM29 nM
In vitro DMSO Warmed: 89 mg/mL (158.77 mM)
Water Insoluble
Ethanol Warmed: 2 mg/mL (3.56 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.84 mL 89.2 mL 178.4 mL
0.5 mM 3.57 mL 17.84 mL 35.68 mL
1 mM 1.78 mL 8.92 mL 17.84 mL
5 mM 0.36 mL 1.78 mL 3.57 mL

*The above data is based on the productmolecular weight 560.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13003
Actions Inhibitor
CAS No. 1361030-48-9
Formula C30H26F2N4O5
M. Wt 560.55
Purity >98%
Synonyms LDC 1267, LDC-1267
SMILES CCOC1=CN(N=C1C(=O)NC2=CC(=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)F)C5=C(C=C(C=C5)F)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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