LDC4297
Catalog No.: A21613
CDK7 inhibitor
LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.
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Biological Activity
| Description | LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM. | ||
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| Targets |
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Product Information
| Catalog Num | A21613 |
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| Formula | C23H28N8O |
| Molecular Weight | 432.52 |
| CAS Number | 1453834-21-3 |
| SMILES | CC(C)C1=C(N2N=C1)N=C(OC3CNCCC3)N=C2NCC4=CC=CC=C4N5C=CC=N5 |
| Synonyms | LDC 4297, LDC-4297 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 78 mg/mL (180.33 mM) | |
| Water | 25 mg/mL (57.8 mM) | ||
| Ethanol | 78 mg/mL (180.33 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.12 mL | 115.6 mL | 231.2 mL |
| 0.5 mM | 4.62 mL | 23.12 mL | 46.24 mL |
| 1 mM | 2.31 mL | 11.56 mL | 23.12 mL |
| 5 mM | 0.46 mL | 2.31 mL | 4.62 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
