LDL-IN-1 is a potent antioxidant that effectively inhibits copper-mediated LDL oxidation, with an IC50 of 52 µM. Additionally, it serves as an inhibitor of Acyl-CoA:cholesterol acyltransferase-1 and -2 (ACAT-1/2), exhibiting IC50 values of 60 µM. This compound is valuable for research into anti-atherosclerotic mechanisms and the modulation of cholesterol metabolism.
LDL-IN-1 is a potent antioxidant that effectively inhibits copper-mediated LDL oxidation, with an IC50 of 52 µM. Additionally, it serves as an inhibitor of Acyl-CoA:cholesterol acyltransferase-1 and -2 (ACAT-1/2), exhibiting IC50 values of 60 µM. This compound is valuable for research into anti-atherosclerotic mechanisms and the modulation of cholesterol metabolism.
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