LDN-211904 oxalate is a potent and reversible inhibitor of EphB3, exhibiting an IC50 of 79 nM. This compound demonstrates favorable metabolic stability in mouse liver microsomes, making it suitable for in vitro studies. LDN-211904 oxalate is particularly relevant for research involving STAT3-activated colorectal cancer stemness and may help overcome Cetuximab resistance in colorectal cancer.
LDN-211904 oxalate is a potent and reversible inhibitor of EphB3, exhibiting an IC50 of 79 nM. This compound demonstrates favorable metabolic stability in mouse liver microsomes, making it suitable for in vitro studies. LDN-211904 oxalate is particularly relevant for research involving STAT3-activated colorectal cancer stemness and may help overcome Cetuximab resistance in colorectal cancer.
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