Fig. 1 · Structure
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Lecufexor
Farnesoid X Receptor Agonist
Lecufexor is a potent agonist of the farnesoid X receptor (FXR). This compound plays a crucial role in regulating bile acid metabolism, glucose homeostasis, and lipid metabolism. It is primarily utilized in research to investigate the therapeutic potential of FXR modulation in metabolic disorders, such as non-alcoholic fatty liver disease and type 2 diabetes. Lecufexor's ability to activate FXR makes it a valuable tool for studying liver function and metabolic regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 2247972-61-6 |
| Applications | Farnesoid X Receptor Agonist |
| Formula | C32H21Cl3N2O5 |
| Molecular Weight | 619.88 |
| SMILES | O=C(C1=CC(C#CC2=CC=C(C=C2Cl)OCC3=C(C4CC4)ON=C3C5=C(Cl)C=CC=C5Cl)=CC6=C1OC(C7CC7)=N6)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.