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Ledasorexton

OX2R Agonist

Ledasorexton is a potent oral agonist of the OX2 receptor (OX2R), exhibiting an EC50 of 0.99 nM. This compound has been demonstrated to induce wakefulness and promote alertness, making it a valuable tool for research into sleep regulation and associated disorders. Its specificity for the OX2R highlights its potential applications in studying neurobiology and pharmacology related to sleep and wakefulness.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	2758363-88-9
Applications	OX2R Agonist
Formula	C₂₂H₃₂FN₅O₂
Molecular Weight	417.52
SMILES	NC([C@@H](C1CC1)N2[C@@]3([H])C[C@]([C@]4([H])[C@@H](CN(C5=NC=C(F)C=N5)CC4)OC)([H])C[C@]2([H])CC3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.