Fig. 1 · Structure

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LEESGGGLVQPGGSMK

Component of Infliximab

LEESGGGLVQPGGSMK is a proteolytic peptide identified as a component of Infliximab, a chimeric monoclonal IgG1 antibody that selectively targets tumor necrosis factor-alpha (TNF-α). This peptide is useful for the quantitative analysis of Infliximab in various biological samples, thereby facilitating research on inflammatory diseases and therapeutic monitoring of TNF-α modulation. Its application in assays enhances the understanding of TNF-α-related pathways and therapeutic interventions in conditions like rheumatoid arthritis and Crohn's disease.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2096980-79-7
Applications Component of Infliximab
Formula C64H108N18O24S
Molecular Weight 1545.71
SMILES
CSCC[C@H](NC(=O)[C@H](CO)NC(=O)CNC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)CNC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CC(C)C)C(C)C)C(=O)N[C@@H](CCCCN)C(O)=O |@@:92|

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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