Fig. 1 · Structure

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Lenalidomide-4-aminomethyl

Ligands for E3 Ligase

Lenalidomide-4-aminomethyl is an E3 ligase ligand that specifically targets cereblon (CRBN), facilitating the recruitment of CRBN protein. This compound serves as an essential building block for the development of PROTAC molecules, enabling targeted protein degradation research. Its unique structural features make it a valuable tool for studying CRBN-mediated pathways and exploring therapeutic applications in cancer and other diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 790652-68-5
Applications Ligands for E3 Ligase
Formula C14H15N3O3
Molecular Weight 273.29
SMILES
O=C(C(N(CC1=C2C=CC=C1CN)C2=O)CC3)NC3=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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