Fig. 1 · Structure

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Lenalidomide 4'-PEG2-amine dihydrochloride

Ligands for E3 Ligase

Lenalidomide 4'-PEG2-amine dihydrochloride is a Cereblon ligand that targets the CRBN protein, playing a crucial role in E3 ligase recruitment. This compound facilitates the development of PROTACs by linking to various target proteins through a suitable linker. It is valuable for research focused on regulated protein degradation pathways and the study of cellular processes influenced by E3 ligase activity.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 2624336-88-3
Applications Ligands for E3 Ligase
Formula C19H28Cl2N4O5
Molecular Weight 463.36
SMILES
O=C1NC(C(CC1)N2C(C3=C(C2)C(NCCOCCOCCN)=CC=C3)=O)=O.Cl.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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