Lenalidomide-5-aminomethyl

Catalog No.: A80589
Ligands for E3 Ligase
Lenalidomide-5-aminomethyl is a cereblon (CRBN) ligand that facilitates the recruitment of the CRBN protein, enabling targeted cellular degradation. This compound can be utilized as a key component in the development of PROTACs (proteolysis-targeting chimeras), which harness the ubiquitin-proteasome system for the selective degradation of specific proteins. Its significant role in E3 ligase-mediated pathways makes it valuable for research in targeted protein modulation and therapeutic development.
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionLenalidomide-5-aminomethyl is a cereblon (CRBN) ligand that facilitates the recruitment of the CRBN protein, enabling targeted cellular degradation. This compound can be utilized as a key component in the development of PROTACs (proteolysis-targeting chimeras), which harness the ubiquitin-proteasome system for the selective degradation of specific proteins. Its significant role in E3 ligase-mediated pathways makes it valuable for research in targeted protein modulation and therapeutic development.
Product Information
Catalog NumA80589
FormulaC14H15N3O3
Molecular Weight273.29
CAS Number1010100-28-3
SMILESO=C(C(N(CC1=C2C=CC(CN)=C1)C2=O)CC3)NC3=O
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