Lenalidomide-5-Br is a derivative of Lenalidomide that functions as a ligand for cereblon (CRBN), an E3 ubiquitin ligase. This compound effectively recruits CRBN to target proteins for ubiquitination and degradation, facilitating the development of Proteolysis Targeting Chimeras (PROTACs). Lenalidomide-5-Br is utilized in research focused on targeted protein degradation and therapeutic development for various diseases, including cancers and autoimmune disorders.
Lenalidomide-5-Br is a derivative of Lenalidomide that functions as a ligand for cereblon (CRBN), an E3 ubiquitin ligase. This compound effectively recruits CRBN to target proteins for ubiquitination and degradation, facilitating the development of Proteolysis Targeting Chimeras (PROTACs). Lenalidomide-5-Br is utilized in research focused on targeted protein degradation and therapeutic development for various diseases, including cancers and autoimmune disorders.
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