Lenalidomide-Br is an analog of the cereblon (CRBN) ligand Lenalidomide, functioning as a ligand for the E3 ubiquitin ligase. This compound effectively recruits the CRBN protein, facilitating targeted protein degradation. Lenalidomide-Br can be utilized to create PROTACs, such as the PROTAC STAT3 degrader SD-36, expanding its application in studies focused on targeted therapy and protein modulation in various biological contexts.
Lenalidomide-Br is an analog of the cereblon (CRBN) ligand Lenalidomide, functioning as a ligand for the E3 ubiquitin ligase. This compound effectively recruits the CRBN protein, facilitating targeted protein degradation. Lenalidomide-Br can be utilized to create PROTACs, such as the PROTAC STAT3 degrader SD-36, expanding its application in studies focused on targeted therapy and protein modulation in various biological contexts.
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