Lenalidomide-propargyl-C2-NH2 hydrochloride is an E3 ligase ligand-linker conjugate that features a cereblon (CRBN) ligand, enabling targeted ubiquitination via the E3 ubiquitin ligase pathway. This compound serves as a critical component in the design of the PROTAC MD-224, facilitating targeted protein degradation. Additionally, Lenalidomide-propargyl-C2-NH2 hydrochloride functions as a click chemistry reagent, characterized by its alkyne group that allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its unique properties make it valuable for research applications focused on protein modulation and degradation.
Lenalidomide-propargyl-C2-NH2 hydrochloride is an E3 ligase ligand-linker conjugate that features a cereblon (CRBN) ligand, enabling targeted ubiquitination via the E3 ubiquitin ligase pathway. This compound serves as a critical component in the design of the PROTAC MD-224, facilitating targeted protein degradation. Additionally, Lenalidomide-propargyl-C2-NH2 hydrochloride functions as a click chemistry reagent, characterized by its alkyne group that allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its unique properties make it valuable for research applications focused on protein modulation and degradation.
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