leniolisib (CDZ 173)

Catalog No.: A16796

PI3K inhibitor

leniolisib (CDZ 173)

leniolisib (CDZ 173) Chemical Structure

CAS NO. 1354690-24-6

Leniolisib(CDZ 173) is a potent PI3Kδ selective inhibitor with biochemical IC50 values of 0.244, 0.424, 2.23 and 0.011 μM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively.

Availability: In stock

Package Price Qty
2 mg
$110.00
5 mg
$190.00
25 mg
$500.00
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Biological Activity

Leniolisib(CDZ 173) is a potent PI3Kδ selective inhibitor with biochemical IC50 values of 0.244, 0.424, 2.23 and 0.011 μM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively.
In vitro DMSO 81 mg/mL (179.81 mM)
Water Insoluble
Ethanol 12 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.2 mL 111 mL 222 mL
0.5 mM 4.44 mL 22.2 mL 44.4 mL
1 mM 2.22 mL 11.1 mL 22.2 mL
5 mM 0.44 mL 2.22 mL 4.44 mL

*The above data is based on the productmolecular weight 450.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16796
Actions Inhibitor
CAS No. 1354690-24-6
Formula C21H25F3N6O2
M. Wt 450.46
Purity >98%
Synonyms Leniolisib; CDZ-173; CDZ 173; CDZ173; Leniosilib
SMILES FC(C1=C(OC)N=CC(N(CCC2=NC=N3)CC2=C3N[[email protected]@H]4CN(C(CC)=O)CC4)=C1)(F)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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