Fig. 1 · Structure
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Lenvatinib-d4
Stable Isotope
Lenvatinib-d4 is a deuterium-labeled derivative of Lenvatinib, a multi-targeted tyrosine kinase inhibitor. It primarily targets vascular endothelial growth factor receptors (VEGFR1-3), fibroblast growth factor receptors (FGFR1-4), platelet-derived growth factor receptor (PDGFR), KIT, and RET, exhibiting strong antitumor activity. This stable isotope is valuable for metabolic studies, pharmacokinetic profiling, and mechanism of action investigations in cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2264050-65-7 |
| Applications | Stable Isotope |
| Formula | C21H15D4ClN4O4 |
| Molecular Weight | 430.88 |
| Synonyms | E7080-d4 |
| SMILES | O=C(C1=C(OC)C=C2N=CC=C(OC3=CC=C(NC(NC4C([2H])(C4([2H])[2H])[2H])=O)C(Cl)=C3)C2=C1)N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.