Leptin (116-130)

Name: Leptin (116-130)
Brand: Adooq Bioscience
SKU: A67340
Rating: 5 (288 reviews)

Catalog No.: A67340

AMPA Receptor Activator

Leptin (116-130) is a bioactive fragment of the leptin protein, known to activate AMPA receptors. This compound enhances AMPA receptor trafficking to synapses, facilitating activity-dependent synaptic plasticity in the hippocampus. Furthermore, Leptin (116-130) exhibits protective effects against synaptic disruption and neuronal cell death in amyloid toxicity models, making it valuable for research into Alzheimer's disease mechanisms.

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Leptin (116-130) 189224-35-9 AMPA Receptor Activator

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Biological Activity

Description

Product Information

Catalog Num	A67340
Formula	C₆₄H₁₀₈N₁₈O₂₅S
Molecular Weight	1561.72
CAS Number	189224-35-9
Sequence shortening	SCSLPQTSGLQKPES
SMILES	C([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CO)N)=O)CS)=O)CO)=O)CC(C)C)=O)CCC1)CCC(N)=O)=O)[C@@H](C)O)=O)CO)=O)=O)CC(C)C)=O)CCC(N)=O)=O)CCCCN)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(O)=O)CO)=O)CCC(O)=O)=O)CCC2

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