Fig. 1 · Structure
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Leriglitazone-d4
Stable Isotope
Leriglitazone-d4 is a deuterium-labeled derivative of Leriglitazone, a potent PPARγ agonist capable of crossing the blood-brain barrier. With an EC50 of 9 μM, it modulates mitochondrial function, exhibiting neuroprotective, anti-inflammatory, and antioxidant properties. This stable isotope is valuable for research investigating neuroinflammatory and neurodegenerative diseases, providing insights into the mechanisms of action and therapeutic potential of PPARγ modulation in neurological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1188263-49-1 |
| Applications | Stable Isotope |
| Formula | C19H16D4N2O4S |
| Molecular Weight | 376.46 |
| Synonyms | MIN-102-d4; Hydroxypioglitazone-d4 |
| SMILES | O=C(NC(S1)=O)C1CC2=C([2H])C([2H])=C(C([2H])=C2[2H])OCCC3=CC=C(C=N3)C(O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.