Lerociclib (G1T38)

Catalog No.: A18320
CDK inhibitor
Lerociclib (G1T38) is a potent and selective inhibitor of CDK4/6, with IC50s of 1 nM, 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively.
Grouped product items
Product Name Price Stock Qty
Lerociclib (G1T38) 5mg
$90.00
In stock
Lerociclib (G1T38) 10mg
$150.00
In stock
Lerociclib (G1T38) 50mg
$650.00
In stock
Lerociclib (G1T38) 100mg
$1,100.00
In stock
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Biological Activity
Discription Lerociclib (G1T38) is a potent and selective inhibitor of CDK4/6, with IC50s of 1 nM, 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively.
Targets
Target Value
Product Information
Catalog Num A18320
Formula C26H34N8O
Molecular Weight 474.613
CAS Number 1628256-23-4
SMILES CC(C)N(CC1)CCN1C(C=N2)=CC=C2NC3=NC=C4C(N(C5(CCCCC5)CNC6=O)C6=C4)=N3
Synonyms G1T-38, G1 T38
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 2 mg/mL (4.21 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.07 mL 105.35 mL 210.7 mL
0.5 mM 4.21 mL 21.07 mL 42.14 mL
1 mM 2.11 mL 10.53 mL 21.07 mL
5 mM 0.42 mL 2.11 mL 4.21 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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