Lesinurad

Catalog No.: A12981

SUR inhibitor

Lesinurad

Lesinurad Chemical Structure

CAS NO. 878672-00-5

Lesinurad is a selective uric acid re-absorption inhibitor (SURI) and is also a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body.

Availability: In stock

Package Price Qty
5 mg
$55.00
10 mg
$75.00
25 mg
$150.00
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Biological Activity

Lesinurad is a selective uric acid re-absorption inhibitor (SURI) and is also a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body.
Targets
URAT1
In vitro DMSO 72 mg/mL (178.09 mM)
Water Insoluble
Ethanol 49 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.74 mL 123.68 mL 247.35 mL
0.5 mM 4.95 mL 24.74 mL 49.47 mL
1 mM 2.47 mL 12.37 mL 24.74 mL
5 mM 0.49 mL 2.47 mL 4.95 mL

*The above data is based on the productmolecular weight 404.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12981
Actions Inhibitor
CAS No. 878672-00-5
Formula C17H14BrN3O2S
M. Wt 404.28
Purity >98%
Synonyms RDEA594, RDEA 594, RDEA-594
SMILES C1CC1C2=CC=C(C3=CC=CC=C23)N4C(=NN=C4Br)SCC(=O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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