Fig. 1 · Structure
Documents & Downloads
Lethedioside A
Hes1 Inhibitor
Lethedioside A is a potent Hes1 inhibitor, exhibiting an IC50 of 9.5 μM. This compound effectively prevents Hes1 dimer formation, thereby modulating downstream signaling pathways. Additionally, Lethedioside A displays limited inhibition of TCF4/β-catenin complex formation and reduces nitric oxide production in activated immune cells, highlighting its potential applications in immunology and developmental biology research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 221289-31-2 |
| Applications | Hes1 Inhibitor |
| Formula | C29H34O15 |
| Molecular Weight | 622.57 |
| SMILES | O=C1C(C(OC(C2=CC(OC)=C(OC)C=C2)=C1)=CC(OC)=C3)=C3O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)CO[C@H]5[C@@H]([C@H]([C@H](O)CO5)O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.