Fig. 1 · Structure
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Leucic acid
Drug Metabolism
Leucic acid (α-Hydroxyisocaproic acid) primarily targets the HCAR2 receptor, influencing metabolic pathways such as AMPK and ERK1/2 phosphorylation. This compound exhibits inhibitory effects on lipid synthesis and promotes fatty acid catabolism, which may contribute to reduced adiposity and enhanced lean mass. Additionally, leucic acid demonstrates anti-inflammatory properties by suppressing the secretion of pro-inflammatory cytokines and attenuating inflammation-related gene expression. Its role in decreasing basal protein synthesis and myotube atrophy makes leucic acid relevant for research in obesity and related metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 498-36-2 |
| Applications | Drug Metabolism |
| Formula | C6H12O3 |
| Molecular Weight | 132.16 |
| Synonyms | α-Hydroxyisocaproic acid |
| SMILES | CC(C)CC(O)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.