Fig. 1 · Structure
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Levobetaxolol
β-Adrenergic Antagonist
Levobetaxolol is a selective β-adrenergic antagonist with high affinity for β1, β2, and β3 receptors, exhibiting IC50 values of 33.2, 2970, and 709 nM, respectively. It effectively reduces intraocular pressure (IOP), making it relevant for glaucoma research. Additionally, Levobetaxolol shows micromolar affinity for L-type calcium channels and has demonstrated protective effects against ischemia/reperfusion injury in rat models. This compound is valuable for studies exploring cardiovascular function and ocular health.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 93221-48-8 |
| Applications | β-Adrenergic Antagonist |
| Formula | C18H29NO3 |
| Molecular Weight | 307.43 |
| Synonyms | (S)-Betaxolol |
| SMILES | O[C@H](COC1=CC=C(C=C1)CCOCC2CC2)CNC(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.