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Biological Activity
Levosimendan is a Ca2+ sensitizer that increases contractile force of the myocardium by enhancing the sensitivity of myofilaments to calcium without increasing intracellular calcium concentration.
Targets
| Cardiac troponin C | ||||
| In vitro (25°C) | DMSO | 48 mg/mL (171.26 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 5% DMSO+40%PEG 300+5%Tween80+50%ddH2O | 4 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.68 mL | 178.39 mL | 356.77 mL |
| 0.5 mM | 7.14 mL | 35.68 mL | 71.35 mL |
| 1 mM | 3.57 mL | 17.84 mL | 35.68 mL |
| 5 mM | 0.71 mL | 3.57 mL | 7.14 mL |
*The above data is based on the productmolecular weight 280.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11874 |
|---|---|
| CAS No. | 141505-33-1 |
| Formula | C14H12N6O |
| M. Wt | 280.29 |
| Purity | >98% |
| SMILES | C[C@@H]1CC(=O)NN=C1C2=CC=C(C=C2)NN=C(C#N)C#N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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