Levosimendan

Catalog No.: A11874

Levosimendan Chemical Structure

CAS NO. 141505-33-1

Levosimendan is a Ca2+ sensitizer that increases contractile force of the myocardium by enhancing the sensitivity of myofilaments to calcium without increasing intracellular calcium concentration.

Availability: In stock

Package Price Qty
100 mg
$50.00
250 mg
$120.00
500 mg
$200.00
1000 mg
$350.00
10mM * 1mL in DMSO
$60.00

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Biological Activity

Levosimendan is a Ca2+ sensitizer that increases contractile force of the myocardium by enhancing the sensitivity of myofilaments to calcium without increasing intracellular calcium concentration.
Targets
Cardiac troponin C
In vitro (25°C) DMSO 56 mg/mL (199.8 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.68 mL 178.39 mL 356.77 mL
0.5 mM 7.14 mL 35.68 mL 71.35 mL
1 mM 3.57 mL 17.84 mL 35.68 mL
5 mM 0.71 mL 3.57 mL 7.14 mL

*The above data is based on the productmolecular weight 280.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11874
M. Wt 280.29
Formula C14H12N6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 141505-33-1
SMILES C[[email protected]@H]1CC(=O)NN=C1C2=CC=C(C=C2)NN=C(C#N)C#N

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