Signaling Pathway
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| Discription | LF3 is a specific inhibitor of canonical Wnt signaling by disrupting the interaction between β-catenin and TCF4 with an IC50 less than 2 μM. |
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| Catalog Num | A16851 |
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| Formula | C20H24N4O2S2 |
| Molecular Weight | 416.56 |
| CAS Number | 664969-54-4 |
| SMILES | S=C(N1CCN(C/C=C/C2=CC=CC=C2)CC1)NC3=CC=C(S(=O)(N)=O)C=C3 |
| Synonyms | LF 3, LF-3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 75 mg/mL (180.05 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 5 mg/mL (12 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.01 mL | 120.03 mL | 240.06 mL |
| 0.5 mM | 4.8 mL | 24.01 mL | 48.01 mL |
| 1 mM | 2.4 mL | 12 mL | 24.01 mL |
| 5 mM | 0.48 mL | 2.4 mL | 4.8 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
