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LFS-1107

CRM1 Inhibitor

LFS-1107 is a reversible inhibitor of CRM1, demonstrating a Kd of 12.5 pM. This compound selectively targets and eliminates extranodal natural killer/T cell lymphoma (ENKTL) cells, making it a valuable tool for cancer research. Its potent inhibition of CRM1 facilitates investigations into therapeutic strategies for lymphomas and other malignancies associated with CRM1 dysregulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1799330-91-8
Applications	CRM1 Inhibitor
Formula	C₁₂H₁₁N₅OS₂
Molecular Weight	305.38
SMILES	O=S(C1=NN=NN1C2=CC=CC=C2)/C=C/CCN=C=S

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.