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LGnRH-III, lamprey

Catalog No.: A60691
GnRH Agonist
LGnRH-III, derived from the sea lamprey, acts as a weak agonist of gonadotropin-releasing hormone (GnRH). This compound has been explored for its potential antitumor activities, making it a valuable tool in cancer research. Its mechanism involves the modulation of hormonal pathways, which may provide insights into therapeutic strategies targeting GnRH receptors in various malignancies.
LGnRH-III, lamprey 147859-97-0 GnRH Agonist
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Size Price Stock Qty
5mg
$245.00
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10mg
$405.00
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLGnRH-III, derived from the sea lamprey, acts as a weak agonist of gonadotropin-releasing hormone (GnRH). This compound has been explored for its potential antitumor activities, making it a valuable tool in cancer research. Its mechanism involves the modulation of hormonal pathways, which may provide insights into therapeutic strategies targeting GnRH receptors in various malignancies.
Product Information
Catalog NumA60691
FormulaC59H74N18O14
Molecular Weight1259.33
CAS Number147859-97-0
Sequence{pGLP}-His-Trp-Ser-His-Asp-Trp-Lys-Pro-Gly-NH2
Sequence shortening{pGLP}-HWSHDWKPG-NH2
SMILESC([C@@H](C(N[C@H](C(=O)N1[C@H](C(NCC(N)=O)=O)CCC1)CCCCN)=O)NC([C@@H](NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@H](CC=3C=4C(NC3)=CC=CC4)NC([C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6)=O)=O)CO)=O)=O)CC(O)=O)=O)C=7C=8C(NC7)=CC=CC8
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Endocrinology-Hormones > GnRH receptor