Fig. 1 · Structure
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LH21
CB1 Receptor Antagonist
LH21 is a potent CB1 receptor antagonist that functions as an in vivo neutral cannabinoid. It effectively reduces food intake and body weight gain in obese Zucker rats, making it a valuable tool for research into appetite regulation and obesity management. Its efficacy as a feeding inhibitor highlights its potential applications in metabolic studies and pharmacological research targeting feeding behaviors.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 611207-11-5 |
| Applications | CB1 Receptor Antagonist |
| Formula | C20H20Cl3N3 |
| Molecular Weight | 408.75 |
| SMILES | CCCCCCC1=NN(C(C2=CC=C(C=C2)Cl)=N1)C3=CC=C(C=C3Cl)Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.