Fig. 1 · Structure

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LI-3948

IP6K Inhibitor

LI-3948 is a potent inhibitor of inositol hexakisphosphate kinases (IP6K) with an IC50 of 15.8 nM. This compound exhibits oral bioavailability and effective permeability across the blood-brain barrier, making it suitable for investigating central nervous system disorders. LI-3948 serves as a valuable tool for exploring the role of IP6K in various neurological conditions and related research applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3024591-38-3
Applications IP6K Inhibitor
Formula C19H16Cl2FN3O3
Molecular Weight 424.25
SMILES
FC1=C(C(N)=O)C=CC(N2)=C1[C@]3(CC[C@H](OC4=NC=C(Cl)C=C4Cl)CC3)C2=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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