Fig. 1 · Structure
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Licarin A
Anti-allergic Agent
Licarin A is a neolignan that acts as an anti-allergic agent by significantly inhibiting the production of TNF-α in dinitrophenyl-human serum albumin (DNP-HSA)-stimulated RBL-2H3 cells, with an IC50 value of 12.6 μM. This compound also reduces the levels of PGD2 and downregulates COX-2 expression, highlighting its potential for exploring the mechanisms underlying allergic responses and inflammatory conditions in research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 51020-86-1 |
| Applications | Anti-allergic Agent |
| Formula | C20H22O4 |
| Molecular Weight | 326.39 |
| Synonyms | (+)-Licarin A |
| SMILES | OC1=CC=C([C@@H]2OC3=C(OC)C=C(/C=C/C)C=C3[C@H]2C)C=C1OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.