Fig. 1 · Structure
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Licostinel
Glycine Receptor Antagonist
Licostinel is a potent antagonist of glycine receptors, exhibiting an IC50 value of 59 nM. This compound demonstrates neuroprotective activity, making it a valuable tool in neurobiology research. It is particularly useful for studies investigating excitatory neurotransmission and related neurodegenerative conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 153504-81-5 |
| Applications | Glycine Receptor Antagonist |
| Formula | C8H3Cl2N3O4 |
| Molecular Weight | 276.04 |
| Synonyms | ACEA-1021 |
| SMILES | O=C1NC2=C(NC1=O)C([N+]([O-])=O)=C(C(Cl)=C2)Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.