Lidocaine-d10 is a deuterium-labeled form of lidocaine, primarily targeting sodium channels through complex voltage and use dependence mechanisms. This compound exhibits notable biological activity by inhibiting the growth, migration, and invasion of gastric carcinoma cells, which is mediated by the up-regulation of miR-145 and subsequent inactivation of the MEK/ERK and NF-κB signaling pathways. Lidocaine-d10 serves as a valuable reagent for research applications related to cardiac arrhythmias and cancer biology.
Lidocaine-d10 is a deuterium-labeled form of lidocaine, primarily targeting sodium channels through complex voltage and use dependence mechanisms. This compound exhibits notable biological activity by inhibiting the growth, migration, and invasion of gastric carcinoma cells, which is mediated by the up-regulation of miR-145 and subsequent inactivation of the MEK/ERK and NF-κB signaling pathways. Lidocaine-d10 serves as a valuable reagent for research applications related to cardiac arrhythmias and cancer biology.
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