Lifitegrast

Catalog No.: A17299

LFA-1 antagonist

Lifitegrast

Lifitegrast Chemical Structure

CAS NO. 1025967-78-5

Lifitegrast (SAR 1118) is an integrin lymphocyte function-associated antigen-1 (LFA-1) antagonist; inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM.

Availability: In stock

Package Price Qty
5 mg
$110.00
10 mg
$160.00
50 mg
$480.00
100 mg
$820.00
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Biological Activity

Lifitegrast (SAR 1118) is an integrin lymphocyte function-associated antigen-1 (LFA-1) antagonist; inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.25 mL 81.24 mL 162.48 mL
0.5 mM 3.25 mL 16.25 mL 32.5 mL
1 mM 1.62 mL 8.12 mL 16.25 mL
5 mM 0.32 mL 1.62 mL 3.25 mL

*The above data is based on the productmolecular weight 615.478. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17299
Actions Antagonist
M. Wt 615.478
Formula C29H24Cl2N2O7S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1025967-78-5
Synonyms SAR-1118; SAR 1118; SAR1118; Lifitegrast, brand name: Xiidra.
SMILES O=C(O)[[email protected]@H](NC(C1=C(Cl)C2=C(CN(C(C3=CC=C4C=COC4=C3)=O)CC2)C=C1Cl)=O)CC5=CC=CC(S(=O)(C)=O)=C5

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